An Investigation into the Value of Venography with Special Reference to Varices in the Lower Limb

In Part I,the history of venography was reviewed, the scope of the Writer's investigations indicated, and some general observations on technique discussed. In Part II, a description was given of the findings in 134 venograms performed on normal legs using different techniques, particular attention being paid to absence of filling and incomplete filling of the deep veins. With regard to the former, it was found that while certain techniques demonstrated patency of the deep circulation from the ankle to the groin in every instance, no technique could be relied on to fill all the deep veins; with regard to the latter, four different ways in which this could occur were described, and it was pointed out that the appearances so produced were indistinguishable from those hitherto ascribed to acute deep thrombophlebitis. It was concluded that, while venography is capable of demonstrating patency of the deep circulation of the leg, it must be extremely unreliable in the diagnosis or exclusion of acute deep thrombophlebitis. In Part III, an account was given of the elaboration in venographic technique required to demonstrate the deep circulation of the leg when the superficial veins are varicose and the ankle oedematous, and, with particular reference to the deep circulation, the results of venograms performed on 36 cases of varicose ulceration, and 26 cases of post-phlebitic ulceration, were described. It was found that the deep circulation was patent from the ankle to the groin in every instance, and that in 11 cases of post-phlebitic ulceration the normal deep veins had been replaced by tortuous leashes of incompetent blood vessels. The clinical and venographic findings were correlated, and it was concluded that, since the superficial varices are not compensatory, a history of deep thrombophlebitis in the leg concerned should not be regarded as a contraindication to radical obliteration of varicose veins. In addition, the results were described of retrograde injection of an opaque medium into the femoral vein in 23 normal legs. It was found that,in 16 instances, extensive retrograde flow occurred, and the conclusion was reached that this finding should not be regarded as indicating congenital incompetence of the valves of the deep veins. In Part IV, techniques for the demonstration of the communicating veins in the lower limb were described, and the appearances of competent and incompetent communicating veins illustrated. The results of venographic examinations performed on 40 patients for the identification of communicating veins in the thigh, and on 35 patients for communicating veins below the knee, were compared with the results of clinical tests, and with the operative findings. It was concluded that venography provides a very accurate method,both for identifying the exact position of communicating veins, and for determining whether or not they are incompetent, although the venographic opinion regarding competency is less reliable for communicating veins below the knee than for those in the thigh. In Part V, a description was given of venographic and clinical investigations on 33 patients suffering from recurrence of varicose veins after the operation of high ligation of the internal saphenous vein. The venographic techniques used in demonstrating the different methods of recurrence were discussed, and the clinical and vemographic results were compared with the operative findings. It was concluded that, in this type of case, venography may be of considerable assistance in clarifying the diagnosis, and so influencing subsequent treatment

On the domain wall partition functions of level-1 affine so(n) vertex models

We derive determinant expressions for domain wall partition functions of level-1 affine so(n) vertex models, n >= 4, at discrete values of the crossing parameter lambda = m pi / 2(n-3), m in Z, in the critical regime.Comment: 14 pages, 13 figures included in latex fil

Game saturation of intersecting families

We consider the following combinatorial game: two players, Fast and Slow, claim $k$-element subsets of $[n]=\{1,2,...,n\}$ alternately, one at each turn, such that both players are allowed to pick sets that intersect all previously claimed subsets. The game ends when there does not exist any unclaimed $k$-subset that meets all already claimed sets. The score of the game is the number of sets claimed by the two players, the aim of Fast is to keep the score as low as possible, while the aim of Slow is to postpone the game's end as long as possible. The game saturation number is the score of the game when both players play according to an optimal strategy. To be precise we have to distinguish two cases depending on which player takes the first move. Let $gsat_F(\mathbb{I}_{n,k})$ and $gsat_S(\mathbb{I}_{n,k})$ denote the score of the saturation game when both players play according to an optimal strategy and the game starts with Fast's or Slow's move, respectively. We prove that $\Omega_k(n^{k/3-5}) \le gsat_F(\mathbb{I}_{n,k}),gsat_S(\mathbb{I}_{n,k}) \le O_k(n^{k-\sqrt{k}/2})$ holds

Latent Space Model for Multi-Modal Social Data

With the emergence of social networking services, researchers enjoy the increasing availability of large-scale heterogenous datasets capturing online user interactions and behaviors. Traditional analysis of techno-social systems data has focused mainly on describing either the dynamics of social interactions, or the attributes and behaviors of the users. However, overwhelming empirical evidence suggests that the two dimensions affect one another, and therefore they should be jointly modeled and analyzed in a multi-modal framework. The benefits of such an approach include the ability to build better predictive models, leveraging social network information as well as user behavioral signals. To this purpose, here we propose the Constrained Latent Space Model (CLSM), a generalized framework that combines Mixed Membership Stochastic Blockmodels (MMSB) and Latent Dirichlet Allocation (LDA) incorporating a constraint that forces the latent space to concurrently describe the multiple data modalities. We derive an efficient inference algorithm based on Variational Expectation Maximization that has a computational cost linear in the size of the network, thus making it feasible to analyze massive social datasets. We validate the proposed framework on two problems: prediction of social interactions from user attributes and behaviors, and behavior prediction exploiting network information. We perform experiments with a variety of multi-modal social systems, spanning location-based social networks (Gowalla), social media services (Instagram, Orkut), e-commerce and review sites (Amazon, Ciao), and finally citation networks (Cora). The results indicate significant improvement in prediction accuracy over state of the art methods, and demonstrate the flexibility of the proposed approach for addressing a variety of different learning problems commonly occurring with multi-modal social data.Comment: 12 pages, 7 figures, 2 table

Cascades: A view from Audience

Cascades on online networks have been a popular subject of study in the past decade, and there is a considerable literature on phenomena such as diffusion mechanisms, virality, cascade prediction, and peer network effects. However, a basic question has received comparatively little attention: how desirable are cascades on a social media platform from the point of view of users? While versions of this question have been considered from the perspective of the producers of cascades, any answer to this question must also take into account the effect of cascades on their audience. In this work, we seek to fill this gap by providing a consumer perspective of cascade. Users on online networks play the dual role of producers and consumers. First, we perform an empirical study of the interaction of Twitter users with retweet cascades. We measure how often users observe retweets in their home timeline, and observe a phenomenon that we term the "Impressions Paradox": the share of impressions for cascades of size k decays much slower than frequency of cascades of size k. Thus, the audience for cascades can be quite large even for rare large cascades. We also measure audience engagement with retweet cascades in comparison to non-retweeted content. Our results show that cascades often rival or exceed organic content in engagement received per impression. This result is perhaps surprising in that consumers didn't opt in to see tweets from these authors. Furthermore, although cascading content is widely popular, one would expect it to eventually reach parts of the audience that may not be interested in the content. Motivated by our findings, we posit a theoretical model that focuses on the effect of cascades on the audience. Our results on this model highlight the balance between retweeting as a high-quality content selection mechanism and the role of network users in filtering irrelevant content

Theory of High-Tc Superconductivity: Accurate Predictions of Tc

The superconducting transition temperatures of high-Tc compounds based on copper, iron, ruthenium and certain organic molecules are discovered to be dependent on bond lengths, ionic valences, and Coulomb coupling between electronic bands in adjacent, spatially separated layers [1]. Optimal transition temperature, denoted as T_c0, is given by the universal expression $k_BT_c0 = e^2 \Lambda / \ell\zeta$; $\ell$ is the spacing between interacting charges within the layers, \zeta is the distance between interacting layers and \Lambda is a universal constant, equal to about twice the reduced electron Compton wavelength (suggesting that Compton scattering plays a role in pairing). Non-optimum compounds in which sample degradation is evident typically exhibit Tc < T_c0. For the 31+ optimum compounds tested, the theoretical and experimental T_c0 agree statistically to within +/- 1.4 K. The elemental high Tc building block comprises two adjacent and spatially separated charge layers; the factor e^2/\zeta arises from Coulomb forces between them. The theoretical charge structure representing a room-temperature superconductor is also presented.Comment: 7 pages 5 references, 6 figures 1 tabl

The Causal Structure of Emotions in Aristotle: Hylomorphism, Causal Interaction between Mind and Body, and Intentionality

Recently, a strong hylomorphic reading of Aristotelian emotions has been put forward, one that allegedly eliminates the problem of causal interaction between soul and body. Taking the presentation of emotions in de An. I 1 as a starting point and basic thread, but relying also on the discussion of Rh. II, I will argue that this reading only takes into account two of the four causes of emotions, and that, if all four of them are included into the picture, then a causal interaction of mind and body remains within Aristotelian emotions, independent of how strongly their hylomorphism is understood. Beyond the discussion with this recent reading, the analysis proposed of the fourfold causal structure of emotions is also intended as a hermeneutical starting point for a comprehensive analysis of particular emotions in Aristotle. Through the different causes Aristotle seems to account for many aspects of the complex phenomenon of emotion, including its physiological causes, its mental causes, and its intentional object

CCR2 and coronary artery disease: a woscops substudy

Background Several lines of evidence support a role for CCL2 (monocyte chemotactic protein-1) and its receptor CCR2 in the development of atherosclerosis. The aim of the present study was to determine the association of the CCR2 Val64Ile polymorphism with the development of coronary artery disease in the WOSCOPS study sample set. Findings A total of 443 cases and 1003 controls from the West of Scotland Coronary Prevention Study (WOSCOPS) were genotyped for the Val64Ile polymorphism in the CCR2 gene. Genotype frequencies were compared between cases and controls. The CCR2 Val64Ile polymorphism was found not to be associated with coronary events in this study population (odds ratio 1.15, 95% CI 0.82-1.61, p = 0.41). Conclusions This case-control study does not support an association of the CCR2 Val64Ile polymorphism with coronary artery disease in the WOSCOPS sample set and does not confirm a possible protective role for CCR2 Val64Ile in the development of coronary artery disease

Exact solutions and stability of rotating dipolar Bose-Einstein condensates in the Thomas-Fermi limit

We present a theoretical analysis of dilute gas Bose-Einstein condensates with dipolar atomic interactions under rotation in elliptical traps. Working in the Thomas-Fermi limit, we employ the classical hydrodynamic equations to first derive the rotating condensate solutions and then consider their response to perturbations. We thereby map out the regimes of stability and instability for rotating dipolar Bose-Einstein condensates and in the latter case, discuss the possibility of vortex lattice formation. We employ our results to propose several novel routes to induce vortex lattice formation in a dipolar condensate.Comment: 12 pages with 6 figure